Mansion Sports – The 2025/2026 LaLiga season once again presents a highly anticipated fixture, as Rayo Vallecano host Real Betis in the Week 16 match.

This encounter is scheduled to take place at the Estadio de Vallecas on Monday, 15 December 2025 at 21.00 local time.

The clash between Rayo Vallecano and Real Betis is expected to be closely contested, as both teams arrive with confidence after securing positive results in European competitions.

Armed with victories in their respective European matches, Rayo Vallecano and Real Betis will face each other in a LaLiga fixture held on Monday at the Estadio de Vallecas.

The hosts are currently positioned 12th in the standings, while Manuel Pellegrini’s side travel to Madrid occupying sixth place.

Before the match kicks off, below is the Mansion Sports prediction for the Rayo Vallecano vs Real Betis December 2025 lineups.

Team Conditions Ahead of the Match

Rayo Vallecano

Rayo are currently experiencing a less convincing run of form in LaLiga, having failed to secure a victory in their last five league matches since recording a narrow 1-0 win over Alaves on 26 October.

After suffering a heavy defeat to Villarreal, Rayo then collected three consecutive LaLiga draws against Real Madrid, Real Oviedo, and Valencia, before eventually falling to a narrow 1-0 away defeat against Espanyol last Sunday.

Nevertheless, they will approach Monday’s match with a degree of confidence after achieving a positive result in the Conference League, following a narrow victory over Jagiellonia Bialystok in Poland on Thursday.

Sergio Camello’s opener was equalised by Jesus Imaz, before substitute Pacha Espino scored just one minute after coming on to secure a 2-1 victory and hand Jagiellonia their first defeat of the main competition phase.

Iñigo Perez’s side, who are currently seventh in the league phase standings, will aim to secure a top-eight position and qualify directly for the round of 16 when they host Drita on Thursday. However, before that, they must first overcome a difficult league test against Betis.

Rayo can also draw confidence from their home record, as they are unbeaten in their last five competitive matches at Vallecas since a 1-0 defeat to Sevilla in September, recording three wins and two draws.

Real Betis

Real Betis will be targeting another victory after recording seven wins from their last 10 matches across all competitions, alongside two draws and one defeat.

However, the sole defeat in that period came in their most recent league match againstBarcelona, where Betis lost 5-3 at their temporary home stadium, La Cartuja.

Los Verdiblancos once again scored three goals in their Europa League match against Dinamo Zagreb on Thursday, with Rodrigo Riquelme and Antony finding the net following a Sergi Dominguez own goal, in a 3-1 victory in Croatia.

That result ensured Betis finished matchday six in fourth place and became one of four teams still unbeaten in the league phase, placing them in a strong position to secure a top-eight finish ahead of their final two matches against PAOK and Feyenoord in January.

Their primary focus is now on ending the calendar year with positive results, as following Monday’s match Betis will face a Copa del Rey fixture against third-division side Real Murcia, before hosting Getafe in their next league outing.

Pellegrini’s side are also unbeaten in 12 competitive away matches this season, and they will look to extend that impressive run while ending a three-match winless streak in their last three meetings with Rayo, consisting of two draws and one defeat.

Rayo Vallecano vs Real Betis Predicted Lineups – December 2025

Rayo Vallecano (4-2-3-1)

The hosts are expected to be without Diego Mendez, Abdul Mumin, Randy Nteka, Pedro Diaz, Oscar Trejo, and Alemao.

Midfielder Unai Lopez must serve a one-match suspension after receiving a red card due to two yellow cards in the defeat against Espanyol.

Rayo have also reached an agreement with the Senegalese Football Federation allowing Pathe Ciss to feature against Betis before joining his national team for Africa Cup of Nations preparations.

Real Betis (4-2-3-1)

For the visitors, Junior Firpo remains sidelined with a hamstring injury, while Hector Bellerin and Isco are not expected to recover in time for this away match.

DR Congo striker Bakambu, along with Moroccan duo Sofyan Amrabat and Abde Ezzalzouli, are also unavailable due to international duties.

Pellegrini is predicted to make several rotations, with Aitor Ruibal, Marc Bartra, Marc Roca, Pablo Fornals, and Cucho Hernandez among the candidates to start.

With both teams in relatively balanced condition, this match is certain to be an engaging contest. 

Knowing the Rayo Vallecano vs Real Betis December 2025 lineups provides a clear picture of the strategies likely to be applied by each coach, while also increasing anticipation ahead of kick-off at the Estadio de Vallecas.