Real Betis vs Real Madrid Lineups September 2026 – Real Madrid will look to extend their perfect start to LaLiga 2026/2027 when they travel to La Cartuja to face Real Betis.

The match is scheduled to take place at Estadio de La Cartuja on Friday, 04 August 2026 at 21:00 local time.

Los Blancos enter the fourth matchweek in second place in La Liga with nine points, level with Barcelona, while the hosts sit seventh after collecting six points from three matches.

Before the match begins, let us take a look at Mansion Sports' prediction for the Real Betis vs Real Madrid lineups September 2026 below.

Both Teams' Conditions Ahead of the Match

Real Betis

Betis are only a few days away from beginning their first Champions League campaign in 21 years after successfully finishing fifth last season.

However, Los Verdiblancos must first overcome a difficult match against Real Madrid before they can shift their focus to their European fixture against Lille in France on Tuesday.

Betis will enter Friday's match on the back of a heavy 5-2 defeat to Levante. The result was quite surprising because they had previously started their campaign with two consecutive 1-0 victories over Real Sociedad and Valencia.

Marc Bartra and Rodrigo Riquelme scored in the first half as Betis repeatedly managed to recover from falling behind.

However, they ultimately failed to respond to two goals from Roger Brugue and Jon Ander Olasagasti's late strike, resulting in their first defeat of the season.

Manuel Pellegrini knows that his team cannot afford to display another weak defensive performance when facing a Real Madrid side that has scored 10 goals in three matches.

Nevertheless, his side should at least be confident of troubling the opposition defence after scoring in 11 consecutive league matches since their goalless draw against Espanyol in April.

Betis will also look to extend their unbeaten home record against Real Madrid.

They have remained unbeaten in their last four meetings against Los Blancos in front of their home supporters, including a dramatic 1-1 draw in April that featured Hector Bellerin's stoppage-time equaliser.

Real Madrid

Meanwhile, Jose Mourinho has enjoyed a successful start to his second spell as Real Madrid manager. The period began with a difficult 2-1 away victory over Espanyol.

Real Madrid have looked more convincing in their first two home matches of the season. They defeated Real Sociedad 4-1 before scoring four more goals in Sunday's match against promoted side Malaga.

Jude Bellingham opened the scoring and then played a major role in Alfonso Herrero's own goal, before Kylian Mbappe scored his 60th La Liga goal to extend Real Madrid's advantage to three goals before the half-hour mark.

Substitute Arda Guler then completed the emphatic victory in the latter stages of the match. The result also meant that Real Madrid have hosted Malaga 18 times in La Liga without ever suffering a defeat, recording 15 wins and three draws.

With Barcelona not playing until Sunday, Mourinho's side will move three points clear at the top of the La Liga table if they can win their away match at Betis for the first time since securing a 1-0 victory in August 2021.

The Portuguese manager has previously experienced mixed results against Los Verdiblancos.

His previous eight meetings have produced four victories, one draw and three defeats, although he won three of the four encounters during his first spell as Real Madrid manager.

Real Betis vs Real Madrid Lineups September 2026

Real Betis (4-2-3-1)

Regarding Real Betis' squad condition, the hosts will be unable to rely on the injured trio of Diego Conde, Aitor Ruibal and Giovani Lo Celso.

Dani Ceballos has returned to Betis on a free transfer from Real Madrid, although a lack of match fitness could prevent him from featuring against his former club.

Pellegrini is expected to make several changes to the team that started in the heavy defeat to Levante. Diego Llorente, Pablo Fornals and Cucho Hernandez are all in contention for places in the starting XI.

Real Madrid (4-2-3-1)

Regarding Real Madrid's squad condition, Mourinho remains unable to call upon Raul Asencio, Ferland Mendy, Thiago Pitarch and Rodrygo due to injuries.

Defender Eder Militao has shown progress in his recovery from a serious hamstring injury, but he is unlikely to return before the international break.

Aurelien Tchouameni and Endrick are the two players closest to returning to action. However, both are still racing against time to prove their fitness in time for Friday's match.

After making changes to the lineup in the convincing victory over Malaga, Mourinho could restore Denzel Dumfries, Ibrahima Konate, Bernardo Silva and Arda Guler to the starting XI for the trip to Andalusia on Friday.

Real Madrid enter this match with high confidence after winning their opening three matches and scoring a total of 10 goals.

However, Betis have a strong home record against Los Blancos and will certainly want to use this match as an opportunity to recover after their heavy defeat to Levante.

With both teams carrying their respective interests, the meeting at La Cartuja has the potential to be a fiercely contested match.

Real Madrid will want to maintain their perfect start while opening a gap at the top of the table, whereas Betis will look to return to winning ways before beginning their Champions League campaign.