Mansion Sports – The 2025/2026 La Liga season begins with a highly anticipated clash between Real Madrid and Osasuna. 

The opening match will take place at the Santiago Bernabéu Stadium on Wednesday, August 20, 2025.

More than just a test of tactics, this encounter serves as a proving ground for two new head coaches eager to make their mark. 

Before kickoff, here is Mansion Sports’ prediction of the starting lineups for Real Madrid vs Osasuna 2025.

Real Madrid Raise Concerns About Preparations

Ahead of the season opener, Real Madrid lodged a formal protest with La Liga authorities. The club expressed dissatisfaction with their preseason schedule, as much of their preparation time was consumed by participation in the 2025 FIFA Club World Cup. 

This situation presents an additional challenge for Xabi Alonso, who has only recently taken charge as head coach.

Osasuna Enter the Season with Calm Confidence

In contrast to their illustrious opponents, Osasuna approach the new campaign with composure. After finishing ninth in the league last season, the team aims to climb higher in the standings.

Interestingly, the Pamplona-based club made few changes during the transfer window, choosing stability over overhaul. 

This consistency could become their key strength when facing one of Spain’s giants.

A Duel of New Managers

This fixture carries extra intrigue as it features two fresh faces in the dugout. Xabi Alonso has already experienced his debut on the touchline with Real Madrid during the FIFA Club World Cup. 

Meanwhile, 39-year-old Alessio Lisci will mark his official debut as Osasuna’s manager in this match.

Predicted Starting Lineups: Real Madrid vs Osasuna 2025

Real Madrid (4-3-3 Formation)

• Goalkeeper: Thibaut Courtois
• Defenders: Trent Alexander-Arnold, Éder Militão, Dean Huijsen, Álvaro Carreras
• Midfielders: Arda Güler, Aurélien Tchouaméni, Federico Valverde
• Forwards: Brahim Díaz, Kylian Mbappé, Vinícius Júnior
• Head Coach: Xabi Alonso

Osasuna (4-3-3 Formation)

• Goalkeeper: Sergio Herrera
• Defenders: Valentin Rosier, Alejandro Catena, Enzo Boyomo, Abel Bretones
• Midfielders: Lucas Torró, Jon Moncayola, Aimar Oroz
• Forwards: Kike Barja, Ante Budimir, Moi Gómez
• Head Coach: Alessio Lisci

This opening fixture represents far more than the pursuit of three points. It is a stage where tactical philosophies and managerial identities will be tested. 

With the confirmed lineups of Real Madrid and Osasuna for 2025, the duel at the Santiago Bernabéu promises intensity and intrigue. 

The lingering question is whether Real Madrid will assert their dominance from the very first whistle, or if Osasuna will deliver a surprise to start the season.