Mansion Sports – The fifth matchday of the 2025/2026 UEFA Champions League presents an intriguing clash between Olympiacos and Real Madrid.

The fixture is scheduled to take place at Karaiskakis Stadium on Wednesday, 26 November 2025, with kickoff set for 22:00 local time.

Real Madrid enter the match seeking to make history by securing their first-ever Champions League victory on Greek soil against Olympiacos.

Los Blancos currently sit seventh in the overall standings with nine points from four matches, while Olympiacos occupy 31st place with just two points.

Team Conditions Ahead of the Match

Olympiacos

The Champions League has been a demanding campaign for Olympiacos this season. From the four matches played, they have recorded two draws and two defeats, placing them 31st in the standings with two points.

José Luis Mendilibar’s side drew with FC Pafos and PSV Eindhoven and suffered defeats to Arsenal and Barcelona.

However, Olympiacos approach this match with renewed confidence after a convincing 3–0 home victory against Atromitos, giving them 28 points from 11 domestic league fixtures and positioning them at the top of the Greek Super League, two points above PAOK.

The Red-and-Whites have shown strong form with four wins in their last five matches across all competitions, remaining unbeaten during that stretch.

Historical trends also favor them at home, as Olympiacos have never lost at home to Real Madrid.

Of their four previous meetings in Greece, three ended in draws—including a goalless match in November 2007—while the Greeks secured a 2–1 victory in December 2005.

Real Madrid

Real Madrid’s four previous wins over Olympiacos have all come at the Santiago Bernabéu, leaving the Spanish giants determined to earn their first away victory against the Greek side.

Despite their ambitions, Xabi Alonso’s team are not in their best form. Since their 4–0 win over Valencia in early November, Los Blancos have gone three matches without a victory, registering two draws and one defeat.

They were held by Rayo Vallecano and Elche in their last two league games but remain at the top of La Liga, one point ahead of Barcelona.

In the Champions League, Real Madrid secured wins over Marseille, Kairat Almaty, and Juventus before a narrow 0–1 defeat to Liverpool. 

Their nine-point tally places them seventh overall. Speculation surrounding Alonso’s future has surfaced, and another disappointing result could further intensify the scrutiny.

Predicted Lineups for Olympiacos vs Real Madrid November 2025

Olympiacos (4-2-3-1)

Olympiacos will once again be without Alexandros Paschalakis and Konstantinos Angelakis due to injuries, although the squad remains largely fit.

Dani Garcia is one booking away from suspension but is still expected to start, supported by his extensive experience facing Real Madrid during his time in La Liga.

Ayoub El Kaabi, who has scored 10 goals in 16 appearances this season, will continue to lead the attack with Daniel Podence featuring on the wing.

Olympiacos Lineup

Real Madrid (4-3-1-2)

Real Madrid will be without Dani Carvajal (knee), Eder Militao (thigh), and Franco Mastantuono (thigh).

The conditions of Antonio Rüdiger (muscle), Aurelien Tchouameni (hamstring), and David Alaba (muscle) will require further assessment.

Alonso is likely to make changes from the squad that played Elche, with Vinicius Junior, Federico Valverde, and Eduardo Camavinga expected to return.

The 4-3-1-2 formation is anticipated, with Jude Bellingham positioned behind the attacking duo of Kylian Mbappé and Vinicius, while Trent Alexander-Arnold could feature again.

Real Madrid Lineup

Closing Remarks

This match promises to deliver a competitive and intense contest shaped by history, ambition, and the individual qualities of both sides.

Spectators can expect a fixture filled with compelling moments as Olympiacos and Real Madrid battle for crucial Champions League points.