Mansion Sports – The fifth matchday of the league phase of the 2025/2026 UEFA Europa League will feature a crucial encounter between AS Roma and Midtjylland, a fixture that could significantly influence both teams’ positions in the standings.

The match is set to take place at the Stadio Olimpico, with kick-off scheduled for Thursday, 27 November 2025 at 18:45 local time.

Following two disappointing home results, AS Roma aim to secure their first home victory of the Europa League campaign, while Midtjylland arrive with a flawless record throughout the competition.

The Danish club have maintained a perfect winning run and currently sit at the top of the table midway through the league phase. Ahead of the match, here is the projected Roma vs Midtjylland lineup from Mansion Sports.

Team Conditions Ahead of the Match

AS Roma

In their most recent Europa League outing, AS Roma claimed a 2-0 victory over Rangers at Ibrox.

Goals from Matias Soule and Lorenzo Pellegrini sealed a second consecutive away win for the Italian capital side.

The result marked Roma’s 99th Europa League victory as they now chase their milestone 100th.

However, Roma’s home performances in European competition this season have been inconsistent. 

After opening with a 2-1 win over Nice, they suffered an unusual defeat to Lille after missing three penalties in a single match, followed by a surprising loss to Viktoria Plzen.

These two defeats matched their total home losses across the previous 38 European games, during which they had secured 28 wins. Roma have also never experienced three consecutive home defeats in European competition.

Roma enter this fixture sitting in the playoff zone and remain well positioned to finish inside the top eight.

Their recent Serie A form has been strong, including a 3-1 win over Cremonese last weekend, extending their winning streak to three matches.

With that momentum, Roma stay atop the Serie A standings and are prepared for a decisive meeting with the Europa League leaders.

Midtjylland

Midtjylland stand as the only team with a perfect record, earning four straight wins to lead the group with 12 points. 

Outside the qualifying rounds, this marks their best showing in European competition. The Danish side also hold the highest number of goals scored and shots on target so far.

Under the guidance of Mike Tullberg, Midtjylland have consistently capitalized on set-piece situations, including their 3-1 win over Celtic in early November where Martin Erlic, Mikel Gogorza, and Franculino each scored.

However, the team suffered a setback in their recent domestic league match, losing 2-1 to Sonderjyske.

Philip Billing received a red card, and the team conceded a penalty in the 100th minute, dropping them to second place in the Danish Superliga, two points behind AGF Aarhus.

The defeat ended their run of 13 matches without a loss, increasing their desire to return to form at the Stadio Olimpico.

Projected Roma vs Midtjylland Lineups for November 2025

AS Roma (3-4-2-1)

Roma will face Napoli at the weekend, which may prompt Gian Piero Gasperini to rotate his squad.

Paulo Dybala and Leon Bailey may return to the bench, while Angelino and Artem Dovbyk remain unavailable. Evan Ferguson is expected to lead the attack after ending his recent goal drought.

AS Roma Starting XI:

Midtjylland (3-4-2-1)

Franculino remains the focal point of Midtjylland’s attack due to his sharp form in both domestic and European competitions.

Billing and Erlic return to Italy as former Serie A players, while Edward Chilufya and Adam Gabriel are still sidelined. Ovie Ejeheri is also doubtful.

Midtjylland Starting XI:

There will be numerous tactical dynamics and individual performances to observe from both sides as they prepare for this high-stakes encounter.